McKim, T.H., Gera, J., Gayban, A. J., Reinhard, N., Manoli, G., Hilpert, S., Helfrich-Förster, C. and Zandawala, M. (2024) Synaptic connectome of a neurosecretory network in the Drosophila brain. eLife (under revision) https://www.biorxiv.org/content/10.1101/2024.08.28.609616v1.
Gera, J., Agard, M.#, Nave, H.#, Sajadi, F., Thorat, L., Kondo, S., Nässel, D., Paluzzi, J.P. and Zandawala, M. (2024) Anti-diuretic hormone ITP signals via a guanylate cyclase receptor to modulate systemic homeostasis in Drosophila. eLife (under revision). https://doi.org/10.7554/eLife.97043.1 (# equal contribution).
Held, M.#, Bisen, R.#, Zandawala, M.#, Chockley, A., Balles, I., Hilpert, S., Liessem, S., Cascino-Milani, F. and Ache, J. (2024) Aminergic and peptidergic modulation of Insulin-Producing Cells in Drosophila. eLife (revised version under review) https://doi.org/10.7554/eLife.99548.1 (# joint first-authors).
Reinhard, N.#, Fukuda, A.#, Manoli, G., Derksen, E., Salto, A., Möller, G., Sekiguchi, M., Rieger, D., Helfrich-Förster, C., Yoshii, T. and Zandawala, M. (2024) Synaptic connectome of the Drosophila circadian clock. Nature Communications (revised version under review). https://www.biorxiv.org/content/10.1101/2023.09.11.557222v2 (# joint first-authors).
Dorkenwald, S., Matsliah, A., Sterling, A., … , Seung, S., Murthy, M. and FlyWire Consortium. (2024) Neuronal wiring diagram of an adult brain. Nature. doi: 10.1038/s41586-024-07558-y. (… middle authors not included).
Schlegel, P., Yin, Y., Bates, A., … , FlyWire Consortium, Costa, M., Seung, S., Murthy, M., Hartenstein, V., Bock, D. and Jefferis, G.S.X.E. (2024) Whole-brain annotation and multi-connectome cell typing quantifies circuit stereotypy in Drosophila. Nature. doi: 10.1038/s41586-024-07686-5. (… middle authors not included).
Agard, M., Zandawala, M. and Paluzzi, J.P. (2024) Another fly diuretic hormone: tachykinins increase fluid and ion transport by adult Drosophila melanogaster Malpighian ‘renal’ tubules. Journal of Experimental Biology. doi: 10.1242/jeb.247668.
Zandawala, M.#, Amir, M. B., Shin, J., Yim, W.C., and Yáñez-Guerra, L.A.# (2024) Proteome-wide neuropeptide identification using NeuroPeptide-HMMer (NP-HMMer). General and Comparative Endocrinology. doi: 10.1016/j.ygcen.2024.114597. (# equal contribution). [PDF]
Hofbauer, B., Zandawala, M., Reinhard, N., Rieger, D., Werner, C., Evers, J.F., Wegener, C. (2024) The neuropeptide pigment-dispersing factor signals independently of Bruchpilot-labelled active zones in daily remodelled terminals of Drosophila clock neurons. European Journal of Neuroscience. doi: 10.1111/ejn.16294. [PDF]
Zandawala, M. and Gera, J. (2024) Leptin- and cytokine-like unpaired signaling in Drosophila. Molecular and Cellular Endocrinology. doi: 10.1016/j.mce.2024.112165. [PDF]
Manoli, G., Zandawala, M., Yoshii, T. and Helfrich-Förster, C. (2023) Characterization of clock-related proteins and neuropeptides in Drosophila littoralis and their putative role in diapause. Journal of Comparative Neurology. doi: 10.1002/cne.25522. [PDF]
Yáñez-Guerra, L.A. and Zandawala, M. (2023) Discovery of paralogous GnRH and corazonin signaling systems in an invertebrate chordate. Genome Biology and Evolution. 15(7): evad108. doi: 10.1093/gbe/evad108. [PDF]
Castelán, N.*, Semmens, D.*, Yáñez-Guerra, L.A.*, Zandawala, M., Barros, M., Slade, S., Scrivens, J., Zampronio, C., Jones, A., Mirabeau, O. and Elphick, M. (2022) Receptor deorphanization in an echinoderm reveals kisspeptin evolution and relationship with SALMFamide neuropeptides. BMC Biology 20: 187. doi: 10.1186/s12915-022-01387-z (* joint first-authors). [PDF]
Nässel, D., and Zandawala, M. (2022) Endocrine cybernetics: neuropeptides as molecular switches in behavioral decisions. Open Biology 12: 220174. doi: 10.1098/rsob.220174. [PDF]
Zandawala, M., Nguyen, T., Segura, M., Johard, H., Amcoff, M., Wegener, C., Paluzzi, J.P., and Nässel, D. (2021) A neuroendocrine pathway modulating osmotic stress in Drosophila. PLoS Genetics. 7(3): e1009425. doi: 10.1371/journal.pgen.1009425. [PDF]
Nässel, D., and Zandawala, M. (2020) Hormonal axes in Drosophila: regulation of hormone release and multiplicity of actions. Cell and Tissue Research. 382: 233-266. [PDF]
Nässel, D., Zandawala, M., Kawada, T., and Satake, H. (2019) Tachykinins: neuropeptides that are ancient, diverse, widespread and functionally pleiotropic. Frontiers in Neuroscience 13: 1262. doi: 10.3389/fnins.2019.01262. [PDF]
Odekunle, E., Semmens, D., Martynyuk, N., Tinoco, A., Garewal, A., Patel, R., Blowes, L., Zandawala, M., Delroisse, J., Slade, S., Scrivens, J., Egertová, M., and Elphick, M. (2019) Ancient role of vasopressin/oxytocin-type neuropeptides as regulators of feeding revealed in an echinoderm. BMC Biology. 17: 60. doi: 10.1186/s12915-019-0680-2. [PDF]
Nässel, D., and Zandawala, M. (2019) Recent advances in neuropeptide signaling in Drosophila, from genes to physiology and behavior. Progress in Neurobiology. 179:101607. [PDF]
Yurgel, M., Kakad, P., Zandawala, M., Nässel, D., Godenschwege, T., and Keene, A. (2019) A single pair of leucokinin neurons are modulated by feeding state and regulate sleep-metabolism interactions. PLoS Biology. 17(2): e2006409. doi: 10.1371/journal.pbio.2006409. [PDF]
Zandawala, M., Yurgel, M., Texada, M., Liao, S., Rewitz, K., Keene, A., and Nässel, D. (2018) Modulation of Drosophila post-feeding physiology and behavior by the neuropeptide leucokinin. PLoS Genetics 14(11): e1007767. doi: 10.1371/journal.pgen.1007767. [PDF]
Zandawala, M., Tian, S., and Elphick, M. (2018) The evolution and nomenclature of GnRH-type and corazonin-type neuropeptide signalling systems. General and Comparative Endocrinology 264: 64-77. [PDF]
Zandawala, M., Marley, R., Davies, S.A., and Nässel, D. (2017) Characterization of a set of abdominal neuroendocrine cells that regulate stress physiology using colocalized diuretic peptides in Drosophila. Cellular and Molecular Life Sciences 75: 1099-1115. [PDF]
Zandawala, M., Moghul, I.*, Yáñez-Guerra, L.A.*, Delroisse, J.*, Abylkassimova, N., Hugall, A., O’Hara, T., and Elphick, M. (2017) Discovery of novel representatives of bilaterian neuropeptide families and reconstruction of neuropeptide precursor evolution in ophiuroid echinoderms. Open Biology 7: 170129. doi: 10.1098/rsob.170129. (* joint second-authors). [PDF]
Yeoh, J.*, Pandit, A.*, Zandawala, M., Nässel, D., Davies, S., and Dow, J. (2017) DINeR- Database for Insect Neuropeptide Research. Insect Biochemistry and Molecular Biology 86: 9-19. (* joint first-authors). [PDF]
Mayorova, T., Tian, S., Cai, W., Semmens, D., Odekunle, E., Zandawala, M., Badi, Y., Rowe, M., Egertová, M., and Elphick, M. (2016) Localization of neuropeptide gene expression in larvae of an echinoderm, the starfish Asterias rubens. Frontiers in Neuroscience. 10: 553. doi: 10.3389/fnins.2016.00553. [PDF]
Kubrak, O., Lushchak, O., Zandawala, M., and Nässel, D. (2016) Systemic corazonin signalling modulates stress responses and metabolism in Drosophila. Open Biology. 6: 160152. doi: 10.1098/rsob.160152. [PDF]
Tian, S.*, Zandawala, M.*, Beets, I., Baytemur, E., Slade, S., Scrivens, J., and Elphick, M. (2016) Urbilaterian origin of paralogous GnRH and corazonin neuropeptide signalling pathways. Scientific Reports. 6: 28788. doi:10.1038/srep28788. (* joint first-authors). [PDF]
Lee, H.R., Zandawala, M., Lange, A., and Orchard, I. (2016) Isolation and characterization of the Corticotropin-releasing factor-related diuretic hormone receptor in Rhodnius prolixus. Cellular Signalling. 28: 1152-1162. [PDF]
Jones, C.*, Zandawala, M.*, Semmens, D., Anderson, S., Hanson, G., Janies, D., and Elphick, M. (2016) Identification of a neuropeptide precursor protein that gives rise to a “cocktail” of peptides that bind Cu(II) and generate metal-linked dimers. Biochimica et Biophysica Acta. 1860: 57-66. (* joint first-authors). [PDF]
Zandawala, M., Haddad, A., Hamoudi, Z., and Orchard, I. (2015) Identification and characterization of the adipokinetic hormone/corazonin-related peptide (ACP) signaling system in Rhodnius prolixus. FEBS Journal. 282: 3603-3617. [PDF]
Paluzzi, J.P., Bhatt, G., Wang, C.H., Zandawala, M., Lange, A., and Orchard, I. (2015) Identification, functional characterization and pharmacological profile of a serotonin type-2b receptor in the medically important insect, Rhodnius prolixus. Frontiers in Neuroscience. 9: 175. doi: 10.3389/fnins.2015.00175. [PDF]
Zandawala, M., Poulos, C., and Orchard, I. (2015) Structure-activity relationships of two Rhodnius prolixus calcitonin-like diuretic hormone analogs. Peptides. 68: 211-213. [PDF]
Zandawala, M., Hamoudi, Z., Lange, A., and Orchard, I. (2015) Adipokinetic hormone signaling system in the Chagas disease vector, Rhodnius prolixus. Insect Molecular Biology. 24: 264-276. [PDF]
Zandawala, M., and Orchard, I. (2015) Identification and functional characterization of FGLamide-related allatostatin receptor in Rhodnius prolixus. Insect Biochemistry and Molecular Biology. 57: 1-10. [PDF]
Zandawala, M., Li, S., Hauser, F., Grimmelikhuijzen, C., and Orchard, I. (2013) Isolation and functional characterization of calcitonin-like diuretic hormone receptors in Rhodnius prolixus. PLoS ONE 8(11): e82466. doi:10.1371/journal.pone.0082466. [PDF]
Zandawala, M., and Orchard, I. (2013) Post-feeding physiology in Rhodnius prolixus: The possible role of FGLamide-related allatostatins. General and Comparative Endocrinology. 194: 311-317. [PDF]
Zandawala, M. (2012) Calcitonin-like diuretic hormones in insects. Insect Biochemistry and Molecular Biology. 42(10): 816-825. [PDF]
Zandawala, M., Lytvyn, Y., Taiakina, D., and Orchard, I. (2012) Cloning of the cDNA, localization, and physiological effects of FGLamide-related allatostatins in the blood-gorging bug, Rhodnius prolixus. Insect Biochemistry and Molecular Biology. 42(1): 10-21. [PDF]
Zandawala, M., Paluzzi, J.P., and Orchard, I. (2011) Isolation and characterization of the cDNA encoding DH31 in the kissing bug, Rhodnius prolixus. Molecular and Cellular Endocrinology. 331: 79-88. [PDF]